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阿賀野市立吉田東伍記念博物館所蔵

The profile of first director
Saburo Ishizuka

Born in Yasudamura, Kitakanbara-gun, Niigata (Current Agano City, Niigata)
1877~1958(Died at the age of 81 years old)
Chairman of Niigata prefecture Dental association,
Director of Japanese United Dental association (Currently Japan dental association),
Director of Daito Bunka University, and Director of Tokyo Dental University, successively.
Elected member of the house of representatives for two terms from 1928
and made an effort for the revision of the Dentist law.
Known as a photographer and organized “Hokuetsu Shayukai”.
The enormous number of photographs back then became a valuable document.

Deepened interchange with Hideyo Noguchi during the school days and continued
the correspondence by the letter until Noguchi died afterward.
Especially, it has been said that he sent a handwritten letter of Noguchi’s mother to him
that prompted temporary homecoming.
At the time of Noguchi’s returning home,
accompanied him to the lectures and courtesy visit each time.
After Noguchi passed away,
founded Hideyo Noguchi Memorial institution to praise his achievement.
As a result of long term study,
he accomplished developing the medicine entrusted by Noguchi.

Interchange between Ishizuka and Dr. Noguchi

Dr. Hideyo Noguchi is well known in the world and praised as a Saint Doctor because of his study of Yellow Fever, Syphilis, and Snake venom though risking his life. He burned his hand in his childhood but as he was helped by medical science, he was determined to pursue the medical field and came to train himself under Mr. Morinosuke Chiwaki (a Dentist in Tokyo).
At that time, he started living together with Mr. Saburo Ishizuka as his senior apprentice. Ever since then they had continued the interchange of the heart for their entire life as if real brothers. When Dr. Noguchi was gaining international fame after moving to the United States with the invitation from Rockefeller Foundation, Ishizuka who was at a study, and treatment as a dentist, accompanied Mr. Morinosuke Chiwaki and went to Mainland China and had dental treatment locally. Above all, he gained a good reputation by having a dental treatment of Yuan Shikai and then had Dental treatments in the various places in the continent.
After returning home, Ishizuka became a dentist in Nagaoka-City, Niigata, his hometown, and chosen as the first Chairman of Niigata prefecture dental association in 1907. Later, he became a Director of Japanese United Dental Association. He opened dental offices and clinics in each place and developed the visiting treatment to not-dentist areas. In addition, he served as a member of the House of Representatives for two terms from 1924 and become a central figure of the revision of the Dentist law.
In those days, dentists were not recognized as doctors but as the engineers, so he became the man of influence for the dentist society as a person who has built the foundation of the dentist society which followed until now. Dr. Hideyo Noguchi is well known in the world and praised as a Saint Doctor because of his study of Yellow Fever, Syphilis, and Snake venom though risking his life. He burned his hand in his childhood but as he was helped by medical science, he was determined to pursue the medical field and came to train himself under Mr. Morinosuke Chiwaki (a Dentist in Tokyo).
At that time, he started living together with Mr. Saburo Ishizuka as his senior apprentice. Ever since then they had continued the interchange of the heart for their entire life as if real brothers. When Dr. Noguchi was gaining international fame after moving to the United States with the invitation from Rockefeller Foundation, Ishizuka who was at a study, and treatment as a dentist, accompanied Mr. Morinosuke Chiwaki and went to Mainland China and had dental treatment locally. Above all, he gained a good reputation by having a dental treatment of Yuan Shikai and then had Dental treatments in the various places in the continent.
After returning home, Ishizuka became a dentist in Nagaoka-City, Niigata, his hometown, and chosen as the first Chairman of Niigata prefecture dental association in 1907. Later, he became a Director of Japanese United Dental Association. He opened dental offices and clinics in each place and developed the visiting treatment to not-dentist areas. In addition, he served as a member of the House of Representatives for two terms from 1924 and become a central figure of the revision of the Dentist law.
In those days, dentists were not recognized as doctors but as the engineers, so he became the man of influence for the dentist society as a person who has built the foundation of the dentist society which followed until now.

Way to the
completion of Platinum・Palladium Nano Colloid

In 1915, Dr. Noguchi returned to Japan, and he and Ishizuka visited his home town Inawashiro in Fukushima. Then they went to Higashiyama hot spring to stay accompanied by his mother and Mr. Sakae Kobayashi, his teacher in his elementary school days. At that night, Mr. Kobayashi asked Dr. Noguchi "Mr. Noguchi, you made a great discovery of medical science but what about that of treatment?" Then Dr. Noguchi replied, "Actually now I am thinking about the realization of fundamental medical science which will be applicable to all kinds of diseases". At that time, he had already a model plan of PAPLAL.

Later, Dr. Noguchi visited Ishizuka Dental Clinic after he had finished his lecture in Nagaoka City, Niigata. Dr. Noguchi told Ishizuka about his model plan after he had zealously inspected the facility of the craft room. "I was earnestly devoted myself to the research of bacteria for more than ten years and unexpectedly I discovered pathogenic bacteria in a great success. As a result of that, I naturally felt the needs of medical science regarding treatment and then I was able to have an almost clear view of it. That is to have the Oxidation-reduction power, which is a characteristic of Platinum group, acted in the tissues of human body. The effect is that it promotes the function of the cells and other parts so that it will extinct all the pathogenic bacteria and waste products strongly attached. As you have a deep experiences and skill in processing Platinum group, can you make Platinum group colloid in place of me?" Then the Doctor left for the United States again.

While Ishizuka was corresponding with Dr. Noguchi to report the progress of the study, in May 1928, Dr. Noguchi passed away because of Yellow fever at Accra in West Africa without seeing the completion of PAPLAL. Ishizuka deeply grieved at the death of his close friend and after several years of research based on Doctor's theory, in succession to his will, finally in 1936, he was able to complete the stable colloidal preparation (PAPLAL).
As Sakae Kobayashi knew the effort over the period and secret story of the development on the part of them well, he praises the achievement of Ishizuka by saying "It is a mystery- wonder that a medicine for all kinds of diseases suitable to describe miraculous medicine was finally completed after spending some 20 years with making a strenuous effort for the world and the way and it is as if Dr.Noguchi has come back again. It's really a great joy that a miraculous medicine of salvation was completed for our country".

Source: Hideyo Noguchi immortal spirit foundation, Hideyo Noguchi memorial association issues In 1915, Dr. Noguchi returned to Japan, and he and Ishizuka visited his home town Inawashiro in Fukushima. Then they went to Higashiyama hot spring to stay accompanied by his mother and Mr. Sakae Kobayashi, his teacher in his elementary school days.
At that night, Mr. Kobayashi asked Dr. Noguchi “Mr. Noguchi, you made a great discovery of medical science but what about that of treatment?” Then Dr. Noguchi replied,” Actually now I am thinking about the realization of fundamental medical science which will be applicable to all kinds of diseases”. At that time, he had already a model plan of “Platinum・Palladium Nano Colloid”.

Later, Dr. Noguchi visited Ishizuka Dental Clinic after he had finished his lecture in Nagaoka City, Niigata. Dr. Noguchi told Ishizuka about his model plan after he had zealously inspected the facility of the craft room. “I was earnestly devoted myself to the research of bacteria for more than ten years and unexpectedly I discovered pathogenic bacteria in a great success. As a result of that, I naturally felt the needs of medical science regarding treatment and then I was able to have an almost clear view of it. That is to have the Oxidation-reduction power, which is a characteristic of Platinum group, acted in the tissues of human body. The effect is that it promotes the function of the cells and other parts so that it will extinct all the pathogenic bacteria and waste products strongly attached. As you have a deep experiences and skill in processing Platinum group, can you make Platinum group colloid in place of me?” Then the Doctor left for the United States again.

While Ishizuka was corresponding with Dr. Noguchi to report the progress of the study, in May 1928, Dr. Noguchi passed away because of Yellow fever at Accra in West Africa without seeing the completion of “Platinum・Palladium Nano Colloid”. Ishizuka deeply grieved at the death of his close friend and after several years of research based on Doctor’s theory, in succession to his will, finally in 1936, he was able to complete the long-awaited “Platinum・Palladium Nano Colloid”.
As Sakae Kobayashi knew the effort over the period and secret story of the development on the part of them well, he praises the achievement of Ishizuka by saying ”It is a mystery- wonder that a medicine for all kinds of diseases suitable to describe miraculous medicine was finally completed after spending some 20 years with making a strenuous effort for the world and the way and it is as if Dr.Noguchi has come back again. It’s really a great joy that a miraculous medicine of salvation was completed for our country”.

Source: Hideyo Noguchi immortal spirit(P35-37), issued by Hideyo Noguchi memorial foundation
on November 3, 1955
Origin of PAPLAL(P10-13), issued by Juseikai on November 9,1956.
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